VALCHLOR® (mechlorethamine) gel is a prescription medicine used on the skin to treat people with Stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma (MF-CTCL) who have received previous skin treatment. It is not known if VALCHLOR is safe and effective in children.

Getting started with VALCHLOR

VALCHLOR gel is a CLEAR medicine for Stage IA/IB MF-CTCL

VALCHLOR is made specifically to help fight the skin symptoms of Stage IA/IB MF-CTCL, and the gel formulation can be applied at home.

VALCHLOR is the first and only FDA-approved gel form of a medicine for patients with Stage IA/IB MF-CTCL who have already been on skin treatment. It received FDA approval after validated testing to prove that it was an effective treatment for up to 12 months.

VALCHLOR is a clinically proven medicine that:

  • Provides mechlorethamine in a gel form
  • Helps clear the signs of MF-CTCL from your skin
  • Can be used at home or wherever you need it
    (Refrigeration required. See handling and storage information.)

It can take time to see results with VALCHLOR

MF-CTCL can be unpredictable. Seeing and feeling the impact of VALCHLOR may take time, but it’s important to stick with the treatment for as long as your doctor recommends.

After 6.5 months, most patients in a clinical trial achieved clearer skin in affected lesions (50% reduction in skin rating score).

Inflammation of your skin (dermatitis) is a common side effect with VALCHLOR

Dermatitis is the most common side effect while using VALCHLOR. Immediately tell your doctor if you develop skin reactions such as redness, swelling, itching, blisters, ulcers, and skin infections. Your doctor can help you manage side effects, including dermatitis (inflammation of the skin), which may help you to continue with your treatment.

  • Do not apply VALCHLOR to your face, genital area, anus, or in skin folds, as there is a high risk for skin irritation in these areas
  • Speak to your doctor or nurse about any concerns with your treatment
  • Immediately tell your doctor or nurse if you see any signs of dermatitis

What to expect when you get your prescription

The VALCHLOR prescription process will be different from what you’ve experienced with other prescription medicines.

When your doctor writes a VALCHLOR prescription for you, the two of you will fill out and sign a form that authorizes a specialty pharmacy to ship VALCHLOR directly to your home.

A nurse from the specialty pharmacy will call you to arrange delivery and answer questions you may have about your prescription.

Throughout your treatment journey, a nurse or pharmacist will reach out to answer questions you may have about VALCHLOR.

Please note that VALCHLOR is not available at your local pharmacy.

VALCHLOR is only offered through a specialty pharmacy, which will help you with all your needs, including providing assistance with your prescription and insurance verification.

Important note: VALCHLOR will not be shipped to your home unless you speak with the nurse to confirm shipment. Then someone has to be present at your home to sign for your delivery of VALCHLOR.