VALCHLOR® (mechlorethamine) gel is a prescription medicine used on the skin (topical) to treat people with Stage IA and IB mycosis fungoides–type cutaneous T-cell lymphoma (MF-CTCL) who have received previous skin treatment. It is not known if VALCHLOR is safe and effective in children.

Getting started with VALCHLOR

VALCHLOR gel is a CLEAR medicine for Stage IA/IB mycosis fungoides–type cutaneous T-cell lymphoma (MF-CTCL)

VALCHLOR is made specifically to help fight the skin symptoms of Stage IA/IB MF-CTCL, and the gel formulation can be applied at home.

VALCHLOR is the first and only FDA-approved gel form of mechlorethamine for patients with Stage IA/IB MF-CTCL who have already been on skin treatment. It received FDA approval after validated testing to prove that it was an effective treatment for up to 12 months.

VALCHLOR is a clinically proven medicine that:

  • Provides mechlorethamine in a topical clear gel form
  • Helps clear the signs of the disease from your skin
  • Is applied topically and is not absorbed into the bloodstream
  • Can be used at home or wherever you need it
    (Refrigeration required. See handling and storage information.)

It may take several months to see results with VALCHLOR

Stage IA/IB MF-CTCL can be unpredictable. Seeing and feeling the impact of VALCHLOR may take time, but it's important to stick with the treatment for as long as your doctor recommends.

Inflammation of your skin (dermatitis) is a common side effect with VALCHLOR

Dermatitis is the most common side effect while using VALCHLOR. Immediately tell your doctor if you develop skin reactions such as redness, swelling, itching, blisters, ulcers, and skin infections. Treatments are available to help manage possible skin irritation. Talk to your doctor to decide what is best for you.

  • Do not apply VALCHLOR to your face, genital area, anus, or in skin folds, as there is a high risk for skin irritation in these areas
  • Speak to your doctor or nurse about any concerns with your treatment
  • Immediately tell your doctor or nurse if you see any signs of dermatitis
  • Tell your healthcare provider if you develop skin reactions such as redness, swelling, itching, blisters, ulcers, and skin infections. Your doctor may adjust the frequency of VALCHLOR application if skin reactions occur

What to expect when you get your prescription

The VALCHLOR prescription process will be different from what you’ve experienced with other prescription medicines.

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When your doctor writes a VALCHLOR prescription for you, the two of you will fill out and sign a form that authorizes a specialty pharmacy to ship VALCHLOR directly to your home.

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A nurse from the specialty pharmacy will call you to arrange delivery and answer questions you may have about your prescription.

Throughout your treatment journey, a nurse or pharmacist will reach out to answer questions you may have about VALCHLOR.

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Please note that VALCHLOR is not available at your local pharmacy.

VALCHLOR is only offered through a specialty pharmacy, which will help you with all your needs, including providing assistance with your prescription and insurance verification.

Important note: VALCHLOR will not be shipped to your home unless you speak with the nurse to confirm shipment. Then someone has to be present at your home to sign for your delivery of VALCHLOR.

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