Getting started with VALCHLOR

VALCHLOR gel is a CLEAR medicine for Stage IA/IB MF-CTCL

VALCHLOR is made specifically to help fight the skin symptoms of Stage IA/IB MF-CTCL, and the gel formulation can be applied at home.

VALCHLOR is the first and only FDA-approved gel form of a medicine for patients with Stage IA/IB MF-CTCL who have already been on skin treatment. It received FDA approval after validated testing to prove that it was an effective treatment for up to 12 months.

VALCHLOR is a clinically proven medicine that:

  • Provides mechlorethamine in a gel form
  • Helps clear the signs of MF-CTCL from your skin
  • Can be used at home or wherever you need it
    (Refrigeration required. See handling and storage information.)

It can take time to see results with VALCHLOR

MF-CTCL can be unpredictable. Seeing and feeling the impact of VALCHLOR may take time, but it’s important to stick with the treatment for as long as your doctor recommends.

After 6.5 months, most patients in a clinical trial achieved clearer skin in affected lesions (50% reduction in skin rating score).

Inflammation of your skin (dermatitis) is a common side effect with VALCHLOR

Dermatitis is the most common side effect while using VALCHLOR. Immediately tell your doctor if you develop skin reactions such as redness, swelling, itching, blisters, ulcers, and skin infections. Your doctor can help you manage side effects, including dermatitis (inflammation of the skin), which may help you to continue with your treatment.

  • Do not apply VALCHLOR to your face, genital area, anus, or in skin folds, as there is a high risk for skin irritation in these areas
  • Speak to your doctor or nurse about any concerns with your treatment
  • Immediately tell your doctor or nurse if you see any signs of dermatitis

What to expect when you get your prescription

The VALCHLOR prescription process will be different from what you’ve experienced with other prescription medicines.

When your doctor writes a VALCHLOR prescription for you, the two of you will fill out and sign a form that authorizes a specialty pharmacy to ship VALCHLOR directly to your home.

A nurse from the specialty pharmacy will call you to arrange delivery and answer questions you may have about your prescription.

Throughout your treatment journey, a nurse or pharmacist will reach out to answer questions you may have about VALCHLOR.

Please note that VALCHLOR is not available at your local pharmacy.

VALCHLOR is only offered through a specialty pharmacy, which will help you with all your needs, including providing assistance with your prescription and insurance verification.

Important note: VALCHLOR will not be shipped to your home unless you speak with the nurse to confirm shipment. Then someone has to be present at your home to sign for your delivery of VALCHLOR.

  • For questions about your prescription, or to arrange your shipment of VALCHLOR, please call 1-855-4-VALCHLOR (1-855-482-5245). VALCHLOR Support representatives are available to help you Monday through Friday from 8 am to 8 pm Eastern Standard Time.

VALCHLOR is a clear gel option to help patients with Stage IA/IB MF-CTCL.
Ask your doctor if VALCHLOR is right for you.

IMPORTANT SAFETY INFORMATION

VALCHLOR® (mechlorethamine) gel is for use on skin only. Do not get VALCHLOR near or in your eyes, mouth, or nose as it can cause pain, redness, swelling, burning, and ulcers. It can also cause sensitivity to light, blurred vision, and may also cause blindness or permanent eye injury. If VALCHLOR gets in your eyes, rinse your eyes right away for at least 15 minutes with a large amount of water, normal saline, or an eyewash solution. If it gets in your nose or mouth, rinse the affected area right away for at least 15 minutes with a large amount of water. Get medical help right away.

Do not use VALCHLOR if you are severely allergic to mechlorethamine. Tell your healthcare provider if you have had an allergic reaction to mechlorethamine.

Before using VALCHLOR, tell your healthcare provider about all your medical conditions. In addition, if you are pregnant, planning a pregnancy, or breastfeeding:

VALCHLOR is flammable. Avoid fire, flame, and smoking until VALCHLOR has dried.

SERIOUS SIDE EFFECTS INCLUDE:

Risk of secondary exposure to VALCHLOR for caregivers who accidentally come into contact with VALCHLOR may include risk of skin inflammation (dermatitis); injury to eyes, mouth, or nose; and certain types of cancer. If accidental contact occurs, wash the affected area with soap and water right away for at least 15 minutes and remove any contaminated clothing. Get medical help right away if VALCHLOR gets in your eyes, mouth, or nose.

Skin inflammation (dermatitis) is common with VALCHLOR and may sometimes be severe. Risk for dermatitis is increased if VALCHLOR is applied to your face, genital area, anus, or skin folds. Tell your healthcare provider if you develop skin reactions such as redness, swelling, itching, blisters, ulcers, and skin infections.

Increased risk of certain types of skin cancers. Certain types of skin cancer can develop on treated and non-treated areas with VALCHLOR. Your healthcare provider will check your skin for skin cancers during and after treatment. Tell your healthcare provider if you get any new skin lesions.

Most common side effects include redness, swelling, itching, skin ulcers or blisters, skin infection, and darkening of areas of your skin.

These are not all the possible side effects of VALCHLOR. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Keep VALCHLOR and all medicines out of the reach of children.

Applying VALCHLOR

When applying VALCHLOR, caregivers must wear disposable nitrile gloves, which should be safely thrown away in the household trash. Wash hands with soap and water after touching or applying VALCHLOR. Apply right away or within 30 minutes once taken out of the refrigerator. Refrigerate VALCHLOR right after each use. Apply a thin layer to completely dry skin at least 4 hours before or 30 minutes after showering or washing. Let treated area dry for 5 to 10 minutes after applying VALCHLOR before covering with clothing. Moisturizers may be applied to the treated areas 2 hours before or 2 hours after applying VALCHLOR. Do not use airtight or watertight bandages on areas treated with VALCHLOR.

Please see full Prescribing Information and Medication Guide for VALCHLOR.

IMPORTANT SAFETY INFORMATION

VALCHLOR® (mechlorethamine) gel is for use on skin only. Do not get VALCHLOR near or in your eyes, mouth, or nose as it can cause pain, redness, swelling, burning, and ulcers. It can also cause sensitivity to light, blurred vision, and may also cause blindness or permanent eye injury. If VALCHLOR gets in your eyes, rinse your eyes right away for at least 15 minutes with a large amount of water, normal saline, or an eyewash solution. If it gets in your nose or mouth, rinse the affected area right away for at least 15 minutes with a large amount of water. Get medical help right away.

Do not use VALCHLOR if you are severely allergic to mechlorethamine. Tell your healthcare provider if you have had an allergic reaction to mechlorethamine.

Before using VALCHLOR, tell your healthcare provider about all your medical conditions. In addition, if you are pregnant, planning a pregnancy, or breastfeeding:

VALCHLOR is flammable. Avoid fire, flame, and smoking until VALCHLOR has dried.

SERIOUS SIDE EFFECTS INCLUDE:

Risk of secondary exposure to VALCHLOR for caregivers who accidentally come into contact with VALCHLOR may include risk of skin inflammation (dermatitis); injury to eyes, mouth, or nose; and certain types of cancer. If accidental contact occurs, wash the affected area with soap and water right away for at least 15 minutes and remove any contaminated clothing. Get medical help right away if VALCHLOR gets in your eyes, mouth, or nose.

Skin inflammation (dermatitis) is common with VALCHLOR and may sometimes be severe. Risk for dermatitis is increased if VALCHLOR is applied to your face, genital area, anus, or skin folds. Tell your healthcare provider if you develop skin reactions such as redness, swelling, itching, blisters, ulcers, and skin infections.

Increased risk of certain types of skin cancers. Certain types of skin cancer can develop on treated and non-treated areas with VALCHLOR. Your healthcare provider will check your skin for skin cancers during and after treatment. Tell your healthcare provider if you get any new skin lesions.

Most common side effects include redness, swelling, itching, skin ulcers or blisters, skin infection, and darkening of areas of your skin.

These are not all the possible side effects of VALCHLOR. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Keep VALCHLOR and all medicines out of the reach of children.

Applying VALCHLOR

When applying VALCHLOR, caregivers must wear disposable nitrile gloves, which should be safely thrown away in the household trash. Wash hands with soap and water after touching or applying VALCHLOR. Apply right away or within 30 minutes once taken out of the refrigerator. Refrigerate VALCHLOR right after each use. Apply a thin layer to completely dry skin at least 4 hours before or 30 minutes after showering or washing. Let treated area dry for 5 to 10 minutes after applying VALCHLOR before covering with clothing. Moisturizers may be applied to the treated areas 2 hours before or 2 hours after applying VALCHLOR. Do not use airtight or watertight bandages on areas treated with VALCHLOR.

Please see full Prescribing Information and Medication Guide for VALCHLOR.